Cancer CRCdb

TF information

TF name:	GLI3
TF family:	zf-C2H2
Ensembl gene ID:	ENSG00000106571
Ensembl protein ID:	ENSP00000379258, ENSP00000496377
Entrez gene ID:	2737

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

Frequency of GLI3 in all biosamples

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Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_02_180	Cell line	Human melanoma	CJM	0.0703125

GLI3 distribution in samples’ most representative CRC

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Sample ID	Tissue type	Biosample type	Biosample name

GLI3 distribution in all CRCs

Genomic distribution of SEs associated with GLI3

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Mutation of GLI3

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Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of GLI3

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
rs139274834	chr7	42085028	42085028	C	T	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
rs751790458	chr7	42004772	42004772	G	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42079723	42079723	G	T	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42004888	42004888	C	A	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	42064869	42064869	C	-	exonic	GLI3	frameshift	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42004024	42004024	C	T	exonic	GLI3	synonymous	SKCM\|1\|368\|0.00272
-	chr7	42063136	42063136	G	T	exonic	GLI3	synonymous	TGCT\|1\|155\|0.00645
-	chr7	42004243	42004243	-	T	exonic	GLI3	frameshift	BRCA\|1\|982\|0.00102
-	chr7	42005532	42005532	G	T	exonic	GLI3	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr7	42005031	42005031	G	A	exonic	GLI3	stopgain	BLCA\|1\|396\|0.00253,LUAD\|1\|543\|0.00184
rs148226583	chr7	42012080	42012080	C	T	exonic	GLI3	synonymous	UCEC\|1\|248\|0.00403
-	chr7	42004345	42004345	C	G	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42007295	42007295	T	C	exonic	GLI3	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr7	42007317	42007317	C	G	exonic	GLI3	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr7	42005620	42005620	G	A	exonic	GLI3	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42088201	42088201	A	T	exonic	GLI3	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr7	42088199	42088199	G	A	exonic	GLI3	synonymous	BLCA\|1\|396\|0.00253
-	chr7	42004980	42004980	G	T	exonic	GLI3	nonsynonymous	BLCA\|2\|396\|0.00505
-	chr7	42004735	42004735	C	A	exonic	GLI3	nonsynonymous	HNSC\|1\|512\|0.00195
rs541487979	chr7	42005114	42005114	G	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42063163	42063163	T	G	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42011989	42011989	A	G	exonic	GLI3	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr7	42006103	42006103	C	T	exonic	GLI3	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42005234	42005234	A	C	exonic	GLI3	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr7	42005257	42005257	G	A	exonic	GLI3	synonymous	LUAD\|1\|543\|0.00184
-	chr7	42004728	42004728	G	T	exonic	GLI3	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr7	42004342	42004342	G	T	exonic	GLI3	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr7	42063167	42063167	T	C	exonic	GLI3	nonsynonymous	LUAD\|2\|543\|0.00368
-	chr7	42004165	42004165	T	A	exonic	GLI3	synonymous	LUSC\|1\|178\|0.00562
-	chr7	42005053	42005053	C	A	exonic	GLI3	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr7	42085089	42085089	C	T	exonic	GLI3	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs765236732	chr7	42005709	42005709	C	T	exonic	GLI3	nonsynonymous	LIHC\|1\|373\|0.00268
rs775586921	chr7	42188023	42188023	C	T	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42012141	42012141	C	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42006172	42006172	G	C	exonic	GLI3	synonymous	LUAD\|1\|543\|0.00184
-	chr7	42262847	42262847	C	A	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42088256	42088256	C	T	exonic	GLI3	synonymous	CESC\|1\|194\|0.00515
-	chr7	42088288	42088288	C	A	exonic	GLI3	nonsynonymous	LUAD\|2\|543\|0.00368
-	chr7	42004926	42004926	A	C	exonic	GLI3	nonsynonymous	PAAD\|1\|185\|0.00541
rs756678135	chr7	42007443	42007443	G	C	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42004786	42004786	G	C	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	42007434	42007434	G	A	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42004800	42004800	C	A	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42006017	42006017	C	A	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42079679	42079679	G	T	exonic	GLI3	stopgain	BRCA\|1\|982\|0.00102
-	chr7	42004460	42004460	A	T	exonic	GLI3	nonsynonymous	CESC\|1\|194\|0.00515
-	chr7	42004819	42004819	G	T	exonic	GLI3	synonymous	LUAD\|1\|543\|0.00184
-	chr7	42018283	42018283	G	T	exonic	GLI3	stopgain	PAAD\|1\|185\|0.00541
-	chr7	42005090	42005090	C	G	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42088245	42088245	C	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42011988	42011988	G	A	exonic	GLI3	nonsynonymous	CESC\|1\|194\|0.00515
-	chr7	42007450	42007450	G	T	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42262807	42262807	-	T	exonic	GLI3	frameshift	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr7	42017268	42017268	C	G	exonic	GLI3	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	42005226	42005226	G	A	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	42004495	42004495	G	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42188011	42188011	G	A	exonic	GLI3	stopgain	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42004360	42004360	C	A	exonic	GLI3	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr7	42012223	42012223	G	A	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	42007413	42007413	T	C	exonic	GLI3	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr7	42004565	42004565	C	T	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
rs376682835	chr7	42005045	42005045	G	A	exonic	GLI3	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	42004984	42004984	C	G	exonic	GLI3	nonsynonymous	CESC\|2\|194\|0.01031
-	chr7	42116408	42116408	G	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42004379	42004379	G	T	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
rs756608797	chr7	42005281	42005281	G	A	exonic	GLI3	synonymous	PAAD\|1\|185\|0.00541,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42011972	42011972	G	A	exonic	GLI3	synonymous	LUSC\|1\|178\|0.00562
-	chr7	42005382	42005382	C	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42011971	42011971	G	T	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs375355919	chr7	42006013	42006013	C	T	exonic	GLI3	synonymous	ESCA\|1\|185\|0.00541,OV\|1\|469\|0.00213
-	chr7	42007509	42007509	T	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs760816574	chr7	42064932	42064932	C	T	exonic	GLI3	synonymous	BRCA\|1\|982\|0.00102
-	chr7	42017211	42017211	A	C	exonic	GLI3	synonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr7	42005077	42005077	G	A	exonic	GLI3	synonymous	SKCM\|1\|368\|0.00272
-	chr7	42005516	42005516	G	A	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	42003980	42003980	G	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253,UCEC\|1\|248\|0.00403
-	chr7	42005961	42005961	G	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253,TGCT\|1\|155\|0.00645
-	chr7	42006174	42006174	G	T	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
rs779595377	chr7	42088290	42088290	G	A	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	42018225	42018225	G	T	exonic	GLI3	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr7	42005959	42005959	G	A	exonic	GLI3	synonymous	ESCA\|1\|185\|0.00541
-	chr7	42006170	42006170	G	A	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	42005045	42005045	G	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42018275	42018275	G	A	exonic	GLI3	stopgain	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs769783770	chr7	42064874	42064874	G	A	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,LUAD\|1\|543\|0.00184
-	chr7	42006006	42006006	C	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42116379	42116379	C	T	exonic	GLI3	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr7	42187973	42187973	C	T	exonic	GLI3	synonymous	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr7	42005573	42005573	G	-	exonic	GLI3	frameshift	COAD\|2\|367\|0.00545,COADREAD\|2\|489\|0.00409,ESCA\|1\|185\|0.00541,STAD\|3\|395\|0.00759,STES\|3\|395\|0.00759
-	chr7	42005764	42005764	G	T	exonic	GLI3	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs929387	chr7	42005678	42005678	G	A	exonic	GLI3	nonsynonymous	ACC\|7\|90\|0.07778
-	chr7	42079725	42079725	G	A	exonic	GLI3	nonsynonymous	HNSC\|1\|512\|0.00195
rs768300131	chr7	42004714	42004714	T	C	exonic	GLI3	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42005592	42005592	G	T	exonic	GLI3	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr7	42003966	42003966	G	C	exonic	GLI3	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr7	42084998	42084998	G	A	exonic	GLI3	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr7	42017206	42017206	G	A	exonic	GLI3	nonsynonymous	BRCA\|1\|982\|0.00102
rs572462647	chr7	42063091	42063091	G	A	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,UCEC\|1\|248\|0.00403
rs121917712	chr7	42012166	42012166	G	A	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42065827	42065827	C	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs112234184	chr7	42005025	42005025	G	T	exonic	GLI3	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr7	42003846	42003846	A	-	UTR3	GLI3	unknown	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42005181	42005181	C	T	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,SKCM\|1\|368\|0.00272,UCEC\|1\|248\|0.00403
-	chr7	42007256	42007256	A	G	exonic	GLI3	nonsynonymous	SARC\|1\|247\|0.00405
-	chr7	42088185	42088185	G	A	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
rs768158142	chr7	42004228	42004228	G	A	exonic	GLI3	synonymous	SKCM\|2\|368\|0.00543
rs751057099	chr7	42262776	42262776	C	T	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	42116409	42116409	C	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42005120	42005120	G	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42005347	42005347	G	A	exonic	GLI3	synonymous	BLCA\|1\|396\|0.00253
-	chr7	42004043	42004043	G	C	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	42005030	42005030	T	G	exonic	GLI3	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr7	42005538	42005538	C	T	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr7	42004239	42004239	C	T	exonic	GLI3	nonsynonymous	ESCA\|1\|185\|0.00541
rs770587326	chr7	42003993	42003993	C	T	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42085011	42085011	G	A	exonic	GLI3	synonymous	ESCA\|1\|185\|0.00541
-	chr7	42152937	42152937	C	A	intronic	GLI3	unknown	OV\|1\|469\|0.00213
-	chr7	42012094	42012094	G	T	exonic	GLI3	synonymous	LIHC\|1\|373\|0.00268
-	chr7	42006192	42006192	G	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42003915	42003915	T	C	UTR3	GLI3	unknown	ESCA\|1\|185\|0.00541
rs766473517	chr7	42064965	42064965	C	T	exonic	GLI3	synonymous	COADREAD\|1\|489\|0.00204,LUAD\|1\|543\|0.00184,READ\|1\|122\|0.00820
rs759525362	chr7	42088262	42088262	C	T	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs531098202	chr7	42005321	42005321	G	A	exonic	GLI3	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	42005706	42005706	G	A	exonic	GLI3	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr7	42005561	42005561	G	A	exonic	GLI3	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	42065860	42065860	G	T	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	42004817	42004817	G	T	exonic	GLI3	nonsynonymous	LUAD\|2\|543\|0.00368
rs772031254	chr7	42005905	42005905	C	T	exonic	GLI3	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs546878700	chr7	42007250	42007250	C	T	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42007481	42007481	C	A	exonic	GLI3	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr7	42065944	42065944	G	A	exonic	GLI3	stopgain	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42088266	42088266	T	A	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42085115	42085115	C	T	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	42065866	42065866	G	T	exonic	GLI3	nonsynonymous	HNSC\|2\|512\|0.00391
-	chr7	42079837	42079837	G	T	exonic	GLI3	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr7	42005081	42005081	A	G	exonic	GLI3	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
-	chr7	42063171	42063171	C	T	exonic	GLI3	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr7	42079655	42079655	A	T	exonic	GLI3	stopgain	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr7	42012029	42012029	C	A	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42005218	42005218	G	A	exonic	GLI3	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42005278	42005278	C	A	exonic	GLI3	synonymous	LUAD\|1\|543\|0.00184
-	chr7	42005464	42005464	G	T	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42005585	42005585	C	T	exonic	GLI3	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	42065865	42065865	G	T	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	42004875	42004875	C	T	exonic	GLI3	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
rs148660482	chr7	42088289	42088289	G	A	exonic	GLI3	synonymous	LUAD\|1\|543\|0.00184
rs530418832	chr7	42004777	42004777	C	T	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs758972863	chr7	42116368	42116368	C	T	exonic	GLI3	synonymous	UCS\|1\|57\|0.01754
rs370676430	chr7	42005292	42005292	C	T	exonic	GLI3	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr7	42064883	42064883	G	A	exonic	GLI3	nonsynonymous	BRCA\|1\|982\|0.00102
rs748621170	chr7	42065950	42065950	G	A	exonic	GLI3	synonymous	SKCM\|1\|368\|0.00272
rs372501575	chr7	42065984	42065984	G	A	exonic	GLI3	synonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr7	42085067	42085067	G	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42006001	42006001	G	A	exonic	GLI3	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42063104	42063104	C	T	exonic	GLI3	nonsynonymous	KIPAN\|2\|799\|0.00250,KIRC\|2\|451\|0.00443
-	chr7	42004149	42004149	C	T	exonic	GLI3	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr7	42005519	42005519	C	A	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42004970	42004970	C	T	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
rs62622373	chr7	42007201	42007201	T	C	exonic	GLI3	nonsynonymous	DLBC\|1\|48\|0.02083
-	chr7	42063103	42063103	G	A	exonic	GLI3	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42003946	42003946	G	A	exonic	GLI3	synonymous	SKCM\|1\|368\|0.00272
-	chr7	42005858	42005858	C	T	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	42005914	42005914	G	C	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42006178	42006178	G	A	exonic	GLI3	synonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189,UCEC\|1\|248\|0.00403
rs564000094	chr7	42012056	42012056	C	G	exonic	GLI3	nonsynonymous	LUAD\|4\|543\|0.00737
-	chr7	42007518	42007518	A	G	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	42005807	42005807	G	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42079765	42079765	G	C	exonic	GLI3	synonymous	ACC\|1\|90\|0.01111
-	chr7	42012008	42012008	C	A	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	42018278	42018278	C	A	exonic	GLI3	stopgain	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42063147	42063147	C	A	exonic	GLI3	stopgain	LUAD\|2\|543\|0.00368
rs767681231	chr7	42005520	42005520	G	A	exonic	GLI3	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr7	42004322	42004322	A	G	exonic	GLI3	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr7	42065849	42065849	A	C	exonic	GLI3	synonymous	LUAD\|1\|543\|0.00184
rs145618226	chr7	42004782	42004782	G	A	exonic	GLI3	synonymous	SKCM\|1\|368\|0.00272
-	chr7	42012087	42012087	G	T	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42064965	42064965	C	A	exonic	GLI3	synonymous	COAD\|2\|367\|0.00545,COADREAD\|3\|489\|0.00613,READ\|1\|122\|0.00820
-	chr7	42004734	42004734	G	A	exonic	GLI3	stopgain	UCEC\|1\|248\|0.00403
-	chr7	42005168	42005168	C	T	exonic	GLI3	nonsynonymous	PAAD\|1\|185\|0.00541
rs780215756	chr7	42079708	42079708	C	T	exonic	GLI3	synonymous	HNSC\|1\|512\|0.00195
-	chr7	42004994	42004994	G	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42012169	42012169	G	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42005251	42005251	G	T	exonic	GLI3	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42005681	42005681	G	A	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42005121	42005121	C	T	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
rs774831772	chr7	42065834	42065834	G	A	exonic	GLI3	synonymous	SKCM\|1\|368\|0.00272
-	chr7	42005160	42005160	C	A	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
rs750890677	chr7	42187878	42187878	C	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42079803	42079803	G	A	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
rs41305933	chr7	42003962	42003962	G	A	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	42005406	42005406	C	T	exonic	GLI3	nonsynonymous	ACC\|1\|90\|0.01111
rs142888674	chr7	42018306	42018306	G	A	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253,UCEC\|3\|248\|0.01210
-	chr7	42004864	42004864	G	A	exonic	GLI3	synonymous	BLCA\|1\|396\|0.00253,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42006129	42006129	C	T	exonic	GLI3	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr7	42063074	42063074	-	GCTGCTCTTGGGTGTCGAACTCCCTC	exonic	GLI3	frameshift	-
-	chr7	42065804	42065804	G	A	exonic	GLI3	synonymous	UCEC\|1\|248\|0.00403
rs765946554	chr7	42005086	42005086	G	A	exonic	GLI3	synonymous	BRCA\|1\|982\|0.00102,LUAD\|1\|543\|0.00184
-	chr7	42116455	42116455	-	T	exonic	GLI3	frameshift	BLCA\|1\|396\|0.00253
-	chr7	42007259	42007259	A	T	exonic	GLI3	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr7	42005127	42005127	G	A	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,PAAD\|1\|185\|0.00541
-	chr7	42005576	42005576	G	A	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
rs535443608	chr7	42007444	42007444	C	T	exonic	GLI3	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42005103	42005103	C	T	exonic	GLI3	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr7	42005670	42005670	C	A	exonic	GLI3	nonsynonymous	HNSC\|1\|512\|0.00195
rs774552566	chr7	42005564	42005564	G	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42017192	42017192	G	A	exonic	GLI3	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr7	42004849	42004849	G	A	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42005448	42005448	G	T	exonic	GLI3	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr7	42005174	42005174	C	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42116418	42116418	G	T	exonic	GLI3	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr7	42007403	42007403	A	T	exonic	GLI3	nonsynonymous	LUAD\|2\|543\|0.00368
-	chr7	42004302	42004302	C	A	exonic	GLI3	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr7	42079819	42079819	G	T	exonic	GLI3	synonymous	KICH\|1\|66\|0.01515,KIPAN\|1\|799\|0.00125
rs761232350	chr7	42085021	42085021	G	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42262748	42262748	G	A	exonic	GLI3	synonymous	LIHC\|1\|373\|0.00268
-	chr7	42012029	42012029	C	T	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42017250	42017250	C	A	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	42004786	42004786	G	A	exonic	GLI3	synonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820,SKCM\|1\|368\|0.00272,UCEC\|1\|248\|0.00403
-	chr7	42004227	42004227	G	A	exonic	GLI3	nonsynonymous	BLCA\|1\|396\|0.00253,SKCM\|1\|368\|0.00272
-	chr7	42005545	42005545	G	A	exonic	GLI3	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs543447540	chr7	42079802	42079802	G	A	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	42007389	42007389	C	T	exonic	GLI3	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	42003945	42003945	G	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42004804	42004804	G	A	exonic	GLI3	synonymous	THYM\|1\|123\|0.00813
-	chr7	42004042	42004042	C	T	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42005006	42005006	G	C	exonic	GLI3	nonsynonymous	LUSC\|1\|178\|0.00562
rs552476301	chr7	42004906	42004906	C	T	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs758875079	chr7	42116431	42116431	G	A	exonic	GLI3	synonymous	SKCM\|1\|368\|0.00272
-	chr7	42005524	42005524	G	C	exonic	GLI3	stopgain	LUAD\|1\|543\|0.00184
-	chr7	42007203	42007203	T	G	exonic	GLI3	nonsynonymous	BRCA\|1\|982\|0.00102
rs758757750	chr7	42064933	42064933	G	A	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42005871	42005871	C	T	exonic	GLI3	nonsynonymous	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr7	42007296	42007296	G	C	exonic	GLI3	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr7	42007370	42007370	G	A	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42005859	42005859	C	T	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	42007402	42007402	G	A	exonic	GLI3	synonymous	BLCA\|1\|396\|0.00253
rs867192776	chr7	42005486	42005486	G	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42005919	42005919	G	A	exonic	GLI3	synonymous	UCEC\|1\|248\|0.00403
-	chr7	42007333	42007333	T	A	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42005202	42005202	C	T	exonic	GLI3	nonsynonymous	BLCA\|1\|396\|0.00253,LUAD\|1\|543\|0.00184
rs781422192	chr7	42012040	42012040	G	A	exonic	GLI3	stopgain	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42005748	42005748	C	G	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
rs779193787	chr7	42006052	42006052	G	T	exonic	GLI3	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
rs762642157	chr7	42005385	42005385	C	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42116424	42116424	G	A	exonic	GLI3	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
-	chr7	42004783	42004783	G	A	exonic	GLI3	synonymous	SKCM\|1\|368\|0.00272
-	chr7	42005604	42005604	G	A	exonic	GLI3	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	42004566	42004566	C	A	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
rs374797309	chr7	42005050	42005050	G	T	exonic	GLI3	nonsynonymous	ACC\|1\|90\|0.01111
-	chr7	42005727	42005727	C	A	exonic	GLI3	nonsynonymous	LUAD\|2\|543\|0.00368
rs569948495	chr7	42005518	42005518	C	T	exonic	GLI3	synonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr7	42004019	42004019	G	C	exonic	GLI3	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr7	42005804	42005804	C	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs761730228	chr7	42005902	42005902	G	A	exonic	GLI3	synonymous	LUSC\|1\|178\|0.00562
-	chr7	42262746	42262746	G	A	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	42004169	42004169	C	A	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42011935	42011935	C	A	splicing	GLI3	splicing	LIHC\|1\|373\|0.00268
rs145479568	chr7	42064901	42064901	C	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42063099	42063099	T	A	exonic	GLI3	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr7	42004738	42004738	G	A	exonic	GLI3	synonymous	UCEC\|1\|248\|0.00403
rs554127075	chr7	42005509	42005509	G	A	exonic	GLI3	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42088263	42088263	G	A	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs770041763	chr7	42005870	42005870	G	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253,UCEC\|1\|248\|0.00403
-	chr7	42005626	42005626	G	A	exonic	GLI3	synonymous	HNSC\|1\|512\|0.00195
-	chr7	42006106	42006106	G	T	exonic	GLI3	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr7	42188061	42188061	T	A	exonic	GLI3	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr7	42005998	42005998	C	T	exonic	GLI3	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs769650527	chr7	42085042	42085042	G	A	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	42005962	42005962	C	A	exonic	GLI3	synonymous	LUAD\|1\|543\|0.00184
rs75313224	chr7	42004065	42004065	A	G	exonic	GLI3	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr7	42011936	42011936	C	T	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	42005555	42005555	G	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs577664817	chr7	42004491	42004491	G	A	exonic	GLI3	nonsynonymous	BLCA\|1\|396\|0.00253
rs186337909	chr7	42085066	42085066	C	T	exonic	GLI3	nonsynonymous	PCPG\|1\|184\|0.00543
-	chr7	42005001	42005001	C	A	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
rs759502281	chr7	42065981	42065981	C	T	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42088216	42088216	C	A	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42017296	42017296	G	C	exonic	GLI3	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr7	42003913	42003913	T	-	UTR3	GLI3	unknown	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr7	42004616	42004616	G	T	exonic	GLI3	stopgain	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42065859	42065859	G	A	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	42007484	42007484	C	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42004974	42004974	T	C	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs776107503	chr7	42012084	42012084	G	A	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
rs745758384	chr7	42085041	42085041	G	A	exonic	GLI3	synonymous	SKCM\|1\|368\|0.00272
-	chr7	42262770	42262770	T	G	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
rs199606102	chr7	42011956	42011956	C	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42005037	42005037	C	T	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42085105	42085105	G	C	exonic	GLI3	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr7	42004440	42004440	C	T	exonic	GLI3	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr7	42065951	42065951	G	A	exonic	GLI3	synonymous	SKCM\|1\|368\|0.00272
-	chr7	42088212	42088212	G	A	exonic	GLI3	nonsynonymous	HNSC\|2\|512\|0.00391
-	chr7	42005488	42005488	G	A	exonic	GLI3	synonymous	LIHC\|1\|373\|0.00268
-	chr7	42005725	42005725	C	A	exonic	GLI3	synonymous	LUSC\|1\|178\|0.00562
-	chr7	42005903	42005903	G	T	exonic	GLI3	nonsynonymous	TGCT\|1\|155\|0.00645
rs757597719	chr7	42012094	42012094	G	A	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	42005113	42005113	C	A	exonic	GLI3	synonymous	BLCA\|1\|396\|0.00253
-	chr7	42017303	42017303	C	T	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42012195	42012195	G	C	exonic	GLI3	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr7	42262804	42262804	C	A	exonic	GLI3	stopgain	BLCA\|1\|396\|0.00253
-	chr7	42005508	42005508	C	T	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42085103	42085103	C	T	exonic	GLI3	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr7	42065886	42065886	G	A	exonic	GLI3	nonsynonymous	BRCA\|1\|982\|0.00102
rs778060205	chr7	42116369	42116369	G	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs377186629	chr7	42004153	42004153	G	A	exonic	GLI3	synonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253,UCEC\|1\|248\|0.00403
rs35448119	chr7	42004897	42004897	G	C	exonic	GLI3	synonymous	DLBC\|1\|48\|0.02083
rs752024375	chr7	42005935	42005935	G	A	exonic	GLI3	synonymous	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr7	42079828	42079828	G	T	exonic	GLI3	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr7	42005569	42005569	C	T	exonic	GLI3	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42005508	42005508	C	A	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
rs749940791	chr7	42088155	42088155	C	T	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs756581886	chr7	42063102	42063102	C	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42262830	42262830	G	C	exonic	GLI3	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr7	42085063	42085063	C	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs139672999	chr7	42007319	42007319	G	A	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs760174184	chr7	42005498	42005498	C	T	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272,UCEC\|1\|248\|0.00403
rs566409623	chr7	42004279	42004279	G	A	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs375277249	chr7	42065983	42065983	C	T	exonic	GLI3	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr7	42005321	42005321	G	T	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	42064977	42064977	C	T	splicing	GLI3	splicing	SKCM\|1\|368\|0.00272
-	chr7	42005877	42005877	T	A	exonic	GLI3	stopgain	LIHC\|1\|373\|0.00268
-	chr7	42079650	42079650	C	T	exonic	GLI3	nonsynonymous	KIPAN\|2\|799\|0.00250,KIRC\|2\|451\|0.00443
-	chr7	42005876	42005876	T	G	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42006218	42006218	C	A	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42085091	42085091	G	A	exonic	GLI3	stopgain	BRCA\|1\|982\|0.00102
-	chr7	42005627	42005627	C	A	exonic	GLI3	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr7	42017203	42017203	T	G	exonic	GLI3	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr7	42005806	42005806	C	T	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs761437755	chr7	42011986	42011986	T	A	exonic	GLI3	stopgain	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42005606	42005606	G	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs748255243	chr7	42005297	42005297	C	A	exonic	GLI3	nonsynonymous	LUSC\|1\|178\|0.00562
rs773038952	chr7	42005906	42005906	G	A	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42004760	42004760	G	T	exonic	GLI3	stopgain	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr7	42079807	42079807	G	T	exonic	GLI3	synonymous	PAAD\|1\|185\|0.00541
rs148502119	chr7	42018305	42018305	C	T	exonic	GLI3	nonsynonymous	PAAD\|1\|185\|0.00541
rs754711120	chr7	42004424	42004424	C	A	exonic	GLI3	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	42005316	42005316	C	A	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	42004993	42004993	T	A	exonic	GLI3	synonymous	LUAD\|1\|543\|0.00184
-	chr7	42005096	42005096	C	A	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
rs757359712	chr7	42064966	42064966	G	A	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,OV\|1\|469\|0.00213
-	chr7	42005278	42005278	C	T	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs532041527	chr7	42017310	42017310	G	A	exonic	GLI3	synonymous	LIHC\|1\|373\|0.00268
-	chr7	42005869	42005869	C	A	exonic	GLI3	synonymous	LUAD\|1\|543\|0.00184
-	chr7	42012031	42012031	G	C	exonic	GLI3	nonsynonymous	BLCA\|1\|396\|0.00253,OV\|1\|469\|0.00213
-	chr7	42262814	42262814	C	A	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
rs774754578	chr7	42065943	42065943	C	T	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	42085000	42085000	T	C	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	42084994	42084994	T	A	exonic	GLI3	nonsynonymous	HNSC\|1\|512\|0.00195
rs747635516	chr7	42005485	42005485	C	T	exonic	GLI3	synonymous	LUSC\|1\|178\|0.00562,STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr7	42017206	42017206	G	C	exonic	GLI3	stopgain	ESCA\|1\|185\|0.00541
-	chr7	42005111	42005111	T	C	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs753656456	chr7	42004413	42004413	C	T	exonic	GLI3	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	42004046	42004046	C	A	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42088194	42088194	G	T	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42004030	42004030	G	A	exonic	GLI3	synonymous	SKCM\|1\|368\|0.00272
-	chr7	42005617	42005617	C	A	exonic	GLI3	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs141220299	chr7	42012081	42012081	G	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253,UCEC\|1\|248\|0.00403
-	chr7	42018254	42018254	A	G	exonic	GLI3	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr7	42079717	42079717	G	A	exonic	GLI3	synonymous	LUAD\|1\|543\|0.00184,SKCM\|1\|368\|0.00272
-	chr7	42004352	42004352	G	T	exonic	GLI3	nonsynonymous	LIHC\|1\|373\|0.00268
rs542238121	chr7	42005299	42005299	G	A	exonic	GLI3	synonymous	PAAD\|1\|185\|0.00541
rs772929930	chr7	42079730	42079730	G	A	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,LUAD\|1\|543\|0.00184,UCEC\|1\|248\|0.00403
-	chr7	42085099	42085099	T	A	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42005301	42005301	G	-	exonic	GLI3	frameshift	LUAD\|1\|543\|0.00184
rs768034418	chr7	42005274	42005274	C	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs752246768	chr7	42079764	42079764	C	T	exonic	GLI3	nonsynonymous	UCEC\|2\|248\|0.00806
-	chr7	42006102	42006102	C	-	exonic	GLI3	frameshift	LIHC\|1\|373\|0.00268
-	chr7	42006214	42006214	G	A	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42005600	42005600	A	C	exonic	GLI3	nonsynonymous	SKCM\|1\|368\|0.00272
rs772276953	chr7	42007393	42007393	G	A	exonic	GLI3	synonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820,UCEC\|2\|248\|0.00806
-	chr7	42006187	42006187	C	T	exonic	GLI3	synonymous	LUAD\|1\|543\|0.00184
-	chr7	42006185	42006185	C	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42005532	42005532	G	A	exonic	GLI3	stopgain	THCA\|1\|504\|0.00198
rs140872736	chr7	42187877	42187877	G	A	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs777201681	chr7	42018290	42018290	C	A	exonic	GLI3	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr7	42005908	42005908	G	A	exonic	GLI3	synonymous	BLCA\|1\|396\|0.00253
rs149860242	chr7	42004666	42004666	C	T	exonic	GLI3	synonymous	UCEC\|1\|248\|0.00403
-	chr7	42085072	42085072	C	T	exonic	GLI3	nonsynonymous	UCEC\|1\|248\|0.00403
rs773316349	chr7	42004496	42004496	C	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42006197	42006197	G	A	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42088271	42088271	A	G	exonic	GLI3	synonymous	UCEC\|1\|248\|0.00403
-	chr7	42018223	42018223	G	A	exonic	GLI3	nonsynonymous	ESCA\|1\|185\|0.00541
rs373918769	chr7	42005798	42005798	G	A	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42079837	42079837	G	A	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42005353	42005353	T	A	exonic	GLI3	synonymous	LUAD\|1\|543\|0.00184
-	chr7	42004014	42004014	T	C	exonic	GLI3	nonsynonymous	UCS\|1\|57\|0.01754
rs776336534	chr7	42004927	42004927	G	A	exonic	GLI3	synonymous	PAAD\|1\|185\|0.00541
-	chr7	42065980	42065980	G	C	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42005853	42005853	G	A	exonic	GLI3	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr7	42005605	42005605	C	T	exonic	GLI3	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253,UCS\|1\|57\|0.01754
-	chr7	42004463	42004463	G	A	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42006024	42006024	C	T	exonic	GLI3	nonsynonymous	CESC\|1\|194\|0.00515
rs763668102	chr7	42085017	42085017	C	A	exonic	GLI3	synonymous	LUAD\|1\|543\|0.00184
-	chr7	42012031	42012031	G	T	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42004594	42004594	C	T	exonic	GLI3	synonymous	UCEC\|1\|248\|0.00403
-	chr7	42005822	42005822	C	T	exonic	GLI3	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	42006047	42006047	C	A	exonic	GLI3	nonsynonymous	LUSC\|1\|178\|0.00562
rs749401038	chr7	42005950	42005950	G	A	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42079752	42079752	C	A	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42004585	42004585	G	A	exonic	GLI3	synonymous	PCPG\|1\|184\|0.00543
-	chr7	42004378	42004378	C	T	exonic	GLI3	synonymous	UCEC\|1\|248\|0.00403
rs778190529	chr7	42005843	42005843	G	A	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs753279069	chr7	42003927	42003927	C	T	UTR3	GLI3	unknown	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs776279429	chr7	42004063	42004063	G	A	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,ESCA\|1\|185\|0.00541
rs774858780	chr7	42187873	42187873	T	C	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	42079690	42079690	A	G	exonic	GLI3	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
rs746798261	chr7	42004061	42004061	C	T	exonic	GLI3	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42065846	42065846	C	A	exonic	GLI3	synonymous	LUSC\|1\|178\|0.00562
rs376725882	chr7	42187951	42187951	C	T	exonic	GLI3	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	42005852	42005852	G	A	exonic	GLI3	nonsynonymous	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr7	42005140	42005140	G	A	exonic	GLI3	synonymous	SKCM\|1\|368\|0.00272
-	chr7	42004503	42004503	C	A	exonic	GLI3	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	42012081	42012081	G	T	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	42004358	42004358	T	G	exonic	GLI3	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253

Disease information of GLI3

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TF_name	Disease_name	Disease_class	Disease_semantic_type	TF_disease_source
GLI3	Craniosynostosis	C05;C16	Disease or Syndrome	GENOMICS_ENGLAND
GLI3	Diastematomyelia	C10;C16	Congenital Abnormality	CTD_human
GLI3	Hydrocephalus	C10	Disease or Syndrome	GENOMICS_ENGLAND
GLI3	Malignant neoplasm of stomach	C04;C06	Neoplastic Process	CTD_human
GLI3	Neural Tube Defects	C10;C16	Congenital Abnormality	CTD_human
GLI3	Neurenteric Cyst	C10;C16	Congenital Abnormality	CTD_human
GLI3	Osteogenesis Imperfecta	C05;C16;C17	Congenital Abnormality; Disease or Syndrome	GENOMICS_ENGLAND
GLI3	Stomach Neoplasms	C04;C06	Neoplastic Process	CTD_human
GLI3	Tethered Cord Syndrome	C10;C16	Disease or Syndrome	CTD_human
GLI3	Iniencephaly	C10;C16	Congenital Abnormality	CTD_human
GLI3	Craniorachischisis	C10;C16	Congenital Abnormality	CTD_human
GLI3	Polydactyly	C05;C16	Congenital Abnormality	CTD_human;GENOMICS_ENGLAND
GLI3	Hypopigmentation disorder	C17	Disease or Syndrome	CTD_human
GLI3	POLYDACTYLY, POSTAXIAL	C05;C16	Disease or Syndrome	CTD_human;UNIPROT
GLI3	Gastrointestinal Stromal Tumors	C04;C06	Neoplastic Process	CTD_human
GLI3	Pallister-Hall syndrome	C04;C05;C10;C16	Disease or Syndrome	CTD_human;ORPHANET
GLI3	Greig cephalopolysyndactyly syndrome	C05;C16	Congenital Abnormality	CTD_human;ORPHANET;UNIPROT
GLI3	Polysyndactyly	C05;C16	Congenital Abnormality	ORPHANET
GLI3	Congenital absence of tibia	C05;C16	Congenital Abnormality	ORPHANET
GLI3	Exencephaly	C10;C16	Congenital Abnormality	CTD_human
GLI3	Hypothalamic hamartomas	C04;C10	Congenital Abnormality	CTD_human;ORPHANET
GLI3	Spinal Cord Myelodysplasia	C10;C16	Congenital Abnormality	CTD_human
GLI3	Epileptic encephalopathy		Disease or Syndrome	GENOMICS_ENGLAND
GLI3	Acrania	C10;C16	Congenital Abnormality	CTD_human
GLI3	Acrocallosal Syndrome	C10;C16	Disease or Syndrome	ORPHANET
GLI3	Colorectal Cancer	C04;C06	Neoplastic Process	UNIPROT
GLI3	Hereditary Diffuse Gastric Cancer	C04;C06	Neoplastic Process	CTD_human
GLI3	Esophageal atresia with or without tracheoesophageal fistula	C06;C08;C16;C23	Disease or Syndrome	CTD_human
GLI3	Polydactyly, preaxial 4	C05;C16	Disease or Syndrome	CTD_human;ORPHANET
GLI3	POSTAXIAL POLYDACTYLY, TYPE B	C05;C16	Disease or Syndrome	CTD_human;ORPHANET;UNIPROT
GLI3	Cakut	C12;C13;C16	Disease or Syndrome	GENOMICS_ENGLAND
GLI3	Acrocallosal syndrome, Schinzel type	C10;C16	Disease or Syndrome	ORPHANET
GLI3	Gastrointestinal Stromal Sarcoma	C04;C06	Neoplastic Process	CTD_human
GLI3	Intellectual Disability	C10;C23;F01;F03	Mental or Behavioral Dysfunction	GENOMICS_ENGLAND
GLI3	Postaxial polydactyly type A	C05;C16	Disease or Syndrome	CTD_human;ORPHANET;UNIPROT
GLI3	Ciliopathies	C16	Congenital Abnormality	GENOMICS_ENGLAND
GLI3	Polydactyly, Postaxial, Type A1	C05;C16	Disease or Syndrome	CTD_human;UNIPROT

Pathway associated with GLI3

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pathway_ID	pathway_name	pathway_source	gene_number	edge_number
pathway0000428	Ci/Gli processing signaling ( Hedgehog signaling pathway )	inoh	17	76
pathway0000756	FAS signaling pathway	panther	37	148
pathway0000906	Gli processing signaling ( Hedgehog signaling pathway )	inoh	15	45
pathway0000907	GLI proteins bind promoters of Hh responsive genes to promote transcription	reactome	7	15
pathway0000908	GLI3 is processed to GLI3R by the proteasome	reactome	59	1548
pathway0000992	Hedgehog off state	reactome	43	309
pathway0000993	Hedgehog on state	reactome	72	1642
pathway0000994	Hedgehog	netpath	39	177
pathway0000996	Hedgehog signaling events mediated by Gli proteins	pid	49	297
pathway0000997	Hedgehog signaling pathway	panther	19	82
pathway0002041	Signaling events mediated by the Hedgehog family	pid	24	77
pathway0002475	Signaling without Hh ( Hedgehog signaling pathway )	inoh	7	20
pathway0002590	Hedgehog signaling pathway	kegg	53	285
pathway0002664	Basal cell carcinoma	kegg	51	551
pathway0002725	Hs_Endochondral_Ossification_WP474_87977	wikipathways	43	117

Go term information of GLI3

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GO_term_name	GO_term_type	TF_name
GO_SPINAL_CORD_DEVELOPMENT	BP	GLI3
GO_MAMMARY_GLAND_MORPHOGENESIS	BP	GLI3
GO_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION	BP	GLI3
GO_REGULATION_OF_CARTILAGE_DEVELOPMENT	BP	GLI3
GO_EMBRYONIC_DIGIT_MORPHOGENESIS	BP	GLI3
GO_THYMIC_T_CELL_SELECTION	BP	GLI3
GO_EMBRYONIC_SKELETAL_SYSTEM_MORPHOGENESIS	BP	GLI3
GO_LAYER_FORMATION_IN_CEREBRAL_CORTEX	BP	GLI3
GO_ARTERY_DEVELOPMENT	BP	GLI3
GO_CRANIAL_NERVE_MORPHOGENESIS	BP	GLI3
GO_VENTRAL_SPINAL_CORD_INTERNEURON_SPECIFICATION	BP	GLI3
GO_CRANIAL_NERVE_DEVELOPMENT	BP	GLI3
GO_CELL_PROLIFERATION_IN_FOREBRAIN	BP	GLI3
GO_POSITIVE_REGULATION_OF_NEUROBLAST_PROLIFERATION	BP	GLI3
GO_TONGUE_DEVELOPMENT	BP	GLI3
GO_SPECIFICATION_OF_ORGAN_IDENTITY	BP	GLI3
GO_CELL_DIFFERENTIATION_IN_SPINAL_CORD	BP	GLI3
GO_SPINAL_CORD_MOTOR_NEURON_DIFFERENTIATION	BP	GLI3
GO_FOREBRAIN_REGIONALIZATION	BP	GLI3
GO_FOREBRAIN_GENERATION_OF_NEURONS	BP	GLI3
GO_FOREBRAIN_CELL_MIGRATION	BP	GLI3
GO_PIGMENTATION	BP	GLI3
GO_NEURAL_PRECURSOR_CELL_PROLIFERATION	BP	GLI3
GO_VENTRAL_SPINAL_CORD_DEVELOPMENT	BP	GLI3
GO_EMBRYONIC_DIGESTIVE_TRACT_MORPHOGENESIS	BP	GLI3
GO_REGULATION_OF_BONE_DEVELOPMENT	BP	GLI3
GO_DIGESTIVE_SYSTEM_DEVELOPMENT	BP	GLI3
GO_ORGAN_FORMATION	BP	GLI3
GO_PROXIMAL_DISTAL_PATTERN_FORMATION	BP	GLI3
GO_POSITIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION	BP	GLI3
GO_SPINAL_CORD_MOTOR_NEURON_CELL_FATE_SPECIFICATION	BP	GLI3
GO_BONE_DEVELOPMENT	BP	GLI3
GO_THYMOCYTE_AGGREGATION	BP	GLI3
GO_EAR_DEVELOPMENT	BP	GLI3
GO_NOSE_DEVELOPMENT	BP	GLI3
GO_CELL_DIFFERENTIATION_INVOLVED_IN_KIDNEY_DEVELOPMENT	BP	GLI3
GO_HIPPOCAMPUS_DEVELOPMENT	BP	GLI3
GO_REGULATION_OF_NEURON_DIFFERENTIATION	BP	GLI3
GO_TELENCEPHALON_GLIAL_CELL_MIGRATION	BP	GLI3
GO_EMBRYONIC_DIGESTIVE_TRACT_DEVELOPMENT	BP	GLI3
GO_RENAL_TUBULE_DEVELOPMENT	BP	GLI3
GO_OPTIC_NERVE_DEVELOPMENT	BP	GLI3
GO_NEURON_FATE_SPECIFICATION	BP	GLI3
GO_BRANCHING_INVOLVED_IN_URETERIC_BUD_MORPHOGENESIS	BP	GLI3
GO_DIGESTIVE_TRACT_MORPHOGENESIS	BP	GLI3
GO_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION	BP	GLI3
GO_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION	BP	GLI3
GO_POSITIVE_REGULATION_OF_NEURAL_PRECURSOR_CELL_PROLIFERATION	BP	GLI3
GO_MESONEPHRIC_TUBULE_MORPHOGENESIS	BP	GLI3
GO_SPINAL_CORD_PATTERNING	BP	GLI3
GO_PIGMENT_CELL_DIFFERENTIATION	BP	GLI3
GO_REGULATION_OF_NEUROBLAST_PROLIFERATION	BP	GLI3
GO_VENTRAL_SPINAL_CORD_INTERNEURON_DIFFERENTIATION	BP	GLI3
GO_NEGATIVE_REGULATION_OF_SMOOTHENED_SIGNALING_PATHWAY	BP	GLI3
GO_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT	BP	GLI3
GO_MAMMARY_GLAND_DEVELOPMENT	BP	GLI3
GO_REGULATION_OF_T_CELL_DIFFERENTIATION	BP	GLI3
GO_DORSAL_VENTRAL_NEURAL_TUBE_PATTERNING	BP	GLI3
GO_POSITIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT	BP	GLI3
GO_POSITIVE_REGULATION_OF_CARTILAGE_DEVELOPMENT	BP	GLI3
GO_LEUKOCYTE_APOPTOTIC_PROCESS	BP	GLI3
GO_REGULATION_OF_SMOOTHENED_SIGNALING_PATHWAY	BP	GLI3
GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION	BP	GLI3
GO_GLIAL_CELL_MIGRATION	BP	GLI3
GO_NEGATIVE_T_CELL_SELECTION	BP	GLI3
GO_DEVELOPMENTAL_PIGMENTATION	BP	GLI3
GO_REGULATION_OF_STEM_CELL_PROLIFERATION	BP	GLI3
GO_NEGATIVE_REGULATION_OF_T_CELL_DIFFERENTIATION	BP	GLI3
GO_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION	BP	GLI3
GO_NEUROEPITHELIAL_CELL_DIFFERENTIATION	BP	GLI3
GO_POSITIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION	BP	GLI3
GO_NEGATIVE_REGULATION_OF_CELL_ADHESION	BP	GLI3
GO_NEGATIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION	BP	GLI3
GO_CEREBRAL_CORTEX_CELL_MIGRATION	BP	GLI3
GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION	BP	GLI3
GO_CRANIOFACIAL_SUTURE_MORPHOGENESIS	BP	GLI3
GO_OLIGODENDROCYTE_DIFFERENTIATION	BP	GLI3
GO_CEREBRAL_CORTEX_RADIALLY_ORIENTED_CELL_MIGRATION	BP	GLI3
GO_POSITIVE_REGULATION_OF_STEM_CELL_PROLIFERATION	BP	GLI3
GO_MELANOCYTE_DIFFERENTIATION	BP	GLI3
GO_CAMERA_TYPE_EYE_MORPHOGENESIS	BP	GLI3
GO_LYMPHOCYTE_APOPTOTIC_PROCESS	BP	GLI3
GO_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION	BP	GLI3
GO_NEGATIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION	BP	GLI3
GO_T_CELL_DIFFERENTIATION	BP	GLI3
GO_POSITIVE_REGULATION_OF_CHONDROCYTE_DIFFERENTIATION	BP	GLI3
GO_SUBPALLIUM_DEVELOPMENT	BP	GLI3
GO_T_CELL_APOPTOTIC_PROCESS	BP	GLI3
GO_NEURAL_TUBE_PATTERNING	BP	GLI3
GO_T_CELL_SELECTION	BP	GLI3
GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION	BP	GLI3
GO_ODONTOGENESIS	BP	GLI3
GO_NEGATIVE_REGULATION_OF_LYMPHOCYTE_DIFFERENTIATION	BP	GLI3
GO_POSITIVE_REGULATION_OF_OSSIFICATION	BP	GLI3
GO_EYE_MORPHOGENESIS	BP	GLI3
GO_CILIARY_TIP	CC	GLI3
GO_TRANSCRIPTIONAL_REPRESSOR_COMPLEX	CC	GLI3
GO_CILIARY_BASE	CC	GLI3
GO_CILIARY_PLASM	CC	GLI3
GO_MEDIATOR_COMPLEX	CC	GLI3
GO_BETA_CATENIN_BINDING	MF	GLI3
GO_HISTONE_DEACETYLASE_BINDING	MF	GLI3
GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING	MF	GLI3
GO_HISTONE_ACETYLTRANSFERASE_BINDING	MF	GLI3

Survival analysis of GLI3

Methods

Overall Survival

Disease Free Survival (RFS)

Group Cutoff

Median

Quartile

Custom

Cutoff-High(%)

Hazards Ratio (HR) Calculate the hazards ratio based on Cox PH Model.

95% Confidence Interval Add the 95% CI as dotted line.

Axis Units

Expression of GLI3

Pan cancer (TCGA) Cell line (ENCODE) In vitro differentiated cell (ENCODE) Primary cell (ENCODE) Tissue (NCBI) Normal tissue (GTEx) Cell line (CCLE)