Cancer CRCdb

Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_02_180	Cell line	Human melanoma	CJM	0.2109375
Sample_02_406	Cell line	Mammary Gland	ZR-75-30_parental	0.44927536231884

Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of MEOX2

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
rs755958618	chr7	15652168	15652168	C	T	exonic	MEOX2	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	15725606	15725606	C	T	exonic	MEOX2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	15725824	15725824	G	C	exonic	MEOX2	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr7	15652091	15652091	G	A	exonic	MEOX2	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr7	15725586	15725586	C	T	exonic	MEOX2	nonsynonymous	BRCA\|1\|982\|0.00102
rs373584566	chr7	15725715	15725715	G	C	exonic	MEOX2	nonsynonymous	THCA\|1\|504\|0.00198
-	chr7	15725983	15725983	C	T	exonic	MEOX2	synonymous	LUAD\|1\|543\|0.00184
-	chr7	15725620	15725620	G	A	exonic	MEOX2	synonymous	COAD\|2\|367\|0.00545,COADREAD\|2\|489\|0.00409
-	chr7	15652155	15652155	C	T	exonic	MEOX2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	15725701	15725701	G	A	exonic	MEOX2	synonymous	UCS\|1\|57\|0.01754
-	chr7	15652107	15652107	C	G	exonic	MEOX2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	15725970	15725970	G	A	exonic	MEOX2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	15700082	15700082	-	TCGA	intronic	MEOX2	unknown	-
-	chr7	15666538	15666538	G	A	exonic	MEOX2	stopgain	BLCA\|1\|396\|0.00253
-	chr7	15666370	15666370	C	T	splicing	MEOX2	splicing	HNSC\|1\|512\|0.00195
-	chr7	15725797	15725797	A	G	exonic	MEOX2	synonymous	COAD\|1\|367\|0.00272,COADREAD\|2\|489\|0.00409,KIPAN\|3\|799\|0.00375,KIRP\|3\|282\|0.01064,READ\|1\|122\|0.00820
-	chr7	15725595	15725595	C	T	exonic	MEOX2	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr7	15666404	15666404	C	G	exonic	MEOX2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	15666537	15666537	T	A	exonic	MEOX2	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	15666539	15666539	G	A	exonic	MEOX2	synonymous	SKCM\|2\|368\|0.00543
-	chr7	15652141	15652141	C	T	exonic	MEOX2	synonymous	SKCM\|1\|368\|0.00272
rs746619188	chr7	15666536	15666536	C	A	exonic	MEOX2	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr7	15666509	15666509	G	A	exonic	MEOX2	synonymous	LUAD\|1\|543\|0.00184
-	chr7	15652076	15652076	C	T	exonic	MEOX2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	15652013	15652013	C	T	exonic	MEOX2	synonymous	SKCM\|1\|368\|0.00272
-	chr7	15652115	15652115	T	G	exonic	MEOX2	nonsynonymous	OV\|1\|469\|0.00213
-	chr7	15652157	15652157	T	C	exonic	MEOX2	nonsynonymous	LUAD\|1\|543\|0.00184
rs753470533	chr7	15725740	15725740	C	T	exonic	MEOX2	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	15666407	15666407	G	C	exonic	MEOX2	stopgain	BLCA\|1\|396\|0.00253
-	chr7	15652018	15652018	G	A	exonic	MEOX2	synonymous	LUAD\|1\|543\|0.00184
-	chr7	15725863	15725863	G	T	exonic	MEOX2	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr7	15652161	15652161	C	T	exonic	MEOX2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	15725827	15725827	C	A	exonic	MEOX2	synonymous	TGCT\|1\|155\|0.00645
-	chr7	15666476	15666476	G	T	exonic	MEOX2	synonymous	LUAD\|1\|543\|0.00184
-	chr7	15725691	15725691	C	T	exonic	MEOX2	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	15725543	15725543	C	T	exonic	MEOX2	nonsynonymous	CESC\|1\|194\|0.00515
-	chr7	15652162	15652162	C	A	exonic	MEOX2	synonymous	LUAD\|1\|543\|0.00184
-	chr7	15652183	15652183	T	C	exonic	MEOX2	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	15725675	15725675	G	-	exonic	MEOX2	frameshift	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	15725770	15725770	C	G	exonic	MEOX2	nonsynonymous	SARC\|1\|247\|0.00405
-	chr7	15725621	15725621	G	C	exonic	MEOX2	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr7	15725557	15725557	C	T	exonic	MEOX2	synonymous	HNSC\|1\|512\|0.00195
-	chr7	15666489	15666489	C	T	exonic	MEOX2	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr7	15725599	15725599	C	A	exonic	MEOX2	synonymous	OV\|1\|469\|0.00213
-	chr7	15725581	15725581	G	T	exonic	MEOX2	stopgain	LUAD\|2\|543\|0.00368
rs868107417	chr7	15652164	15652164	G	A	exonic	MEOX2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	15725656	15725656	C	T	exonic	MEOX2	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	15725928	15725928	C	A	exonic	MEOX2	nonsynonymous	LUAD\|1\|543\|0.00184
rs141784602	chr7	15725538	15725538	C	T	exonic	MEOX2	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr7	15652220	15652220	T	A	exonic	MEOX2	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr7	15652023	15652023	C	A	exonic	MEOX2	nonsynonymous	LUAD\|2\|543\|0.00368
-	chr7	15725735	15725735	G	C	exonic	MEOX2	nonsynonymous	UCS\|1\|57\|0.01754
rs759767365	chr7	15725591	15725591	G	A	exonic	MEOX2	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	15725867	15725867	G	C	exonic	MEOX2	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
rs867233014	chr7	15666531	15666531	C	T	exonic	MEOX2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	15652196	15652196	C	A	exonic	MEOX2	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr7	15652020	15652020	G	A	exonic	MEOX2	nonsynonymous	BLCA\|2\|396\|0.00505
-	chr7	15652223	15652223	A	C	exonic	MEOX2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	15652017	15652017	A	G	exonic	MEOX2	synonymous	HNSC\|1\|512\|0.00195
-	chr7	15666539	15666539	G	C	exonic	MEOX2	synonymous	LUAD\|1\|543\|0.00184
-	chr7	15725811	15725811	G	A	exonic	MEOX2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	15725588	15725588	C	T	exonic	MEOX2	nonsynonymous	SKCM\|1\|368\|0.00272
rs777058351	chr7	15652021	15652021	C	T	exonic	MEOX2	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,ESCA\|1\|185\|0.00541,GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189,LUAD\|1\|543\|0.00184,STAD\|3\|395\|0.00759,STES\|3\|395\|0.00759
-	chr7	15725593	15725593	C	T	exonic	MEOX2	synonymous	ESCA\|1\|185\|0.00541
-	chr7	15725582	15725582	T	C	exonic	MEOX2	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr7	15652098	15652098	C	A	exonic	MEOX2	nonsynonymous	LUAD\|1\|543\|0.00184
rs774347485	chr7	15725800	15725800	G	A	exonic	MEOX2	synonymous	KIPAN\|3\|799\|0.00375,KIRP\|3\|282\|0.01064
-	chr7	15652188	15652188	C	T	exonic	MEOX2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	15652113	15652113	G	A	exonic	MEOX2	synonymous	LUAD\|1\|543\|0.00184
-	chr7	15666406	15666406	C	T	exonic	MEOX2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	15725877	15725877	C	T	exonic	MEOX2	nonsynonymous	CESC\|1\|194\|0.00515,LUAD\|1\|543\|0.00184
-	chr7	15652118	15652118	G	C	exonic	MEOX2	stopgain	BLCA\|1\|396\|0.00253
-	chr7	15725862	15725862	C	T	exonic	MEOX2	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr7	15652156	15652156	C	G	exonic	MEOX2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr7	15725809	15725809	G	A	exonic	MEOX2	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr7	15652133	15652133	C	T	exonic	MEOX2	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr7	15666503	15666503	T	A	exonic	MEOX2	nonsynonymous	STAD\|2\|395\|0.00506,STES\|2\|395\|0.00506
-	chr7	15725719	15725719	C	A	exonic	MEOX2	synonymous	LUAD\|1\|543\|0.00184
-	chr7	15725982	15725982	C	T	exonic	MEOX2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	15666460	15666460	C	A	exonic	MEOX2	stopgain	UCEC\|1\|248\|0.00403
-	chr7	15725803	15725803	G	A	exonic	MEOX2	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204,ESCA\|1\|185\|0.00541,KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355,LIHC\|1\|373\|0.00268
-	chr7	15725799	15725800	GG	-	exonic	MEOX2	frameshift	CESC\|1\|194\|0.00515,UCEC\|1\|248\|0.00403
-	chr7	15652089	15652089	G	T	exonic	MEOX2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	15725885	15725885	C	T	exonic	MEOX2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr7	15725601	15725601	C	T	exonic	MEOX2	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr7	15666529	15666529	T	G	exonic	MEOX2	nonsynonymous	ESCA\|1\|185\|0.00541
-	chr7	15725704	15725704	G	T	exonic	MEOX2	synonymous	HNSC\|2\|512\|0.00391
-	chr7	15725988	15725988	C	T	exonic	MEOX2	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr7	15725510	15725510	C	T	splicing	MEOX2	splicing	UCEC\|1\|248\|0.00403
-	chr7	15652213	15652213	C	A	exonic	MEOX2	nonsynonymous	LUAD\|3\|543\|0.00552
-	chr7	15725539	15725539	G	T	exonic	MEOX2	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253

TF name:	MEOX2
TF family:	Homeobox
Ensembl gene ID:	ENSG00000106511
Ensembl protein ID:	ENSP00000262041
Entrez gene ID:	4223

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

TF_name	Disease_name	Disease_class	Disease_semantic_type	TF_disease_source
MEOX2	Liver Cirrhosis, Experimental	C06	Experimental Model of Disease	CTD_human
MEOX2	Myocardial Ischemia	C14	Disease or Syndrome	CTD_human

GO_term_name	GO_term_type	TF_name
GO_EMBRYONIC_PATTERN_SPECIFICATION	BP	MEOX2
GO_SOMITOGENESIS	BP	MEOX2
GO_SEGMENTATION	BP	MEOX2
GO_SEGMENT_SPECIFICATION	BP	MEOX2
GO_NEURON_DEATH	BP	MEOX2
GO_NUCLEAR_BODY	CC	MEOX2
GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_DISTAL_ENHANCER_SEQUENCE_SPECIFIC_BINDING	MF	MEOX2
GO_ENHANCER_BINDING	MF	MEOX2
GO_RNA_POLYMERASE_II_DISTAL_ENHANCER_SEQUENCE_SPECIFIC_DNA_BINDING	MF	MEOX2

TF information

TCGA somatic mutations and clinical variants of MEOX2

Survival analysis of MEOX2

Expression of MEOX2