Cancer CRCdb

Sample ID	Biosample type	Tissue type	Biosample name	TF Frequency
Sample_02_181	Cell line	Human melanoma	COLO679	0.74453333333333
Sample_02_183	Cell line	Skin	SKMEL2	0.23076923076923
Sample_02_184	Cell line	Skin	SKMEL30	0.37299035369775

Sample ID	Tissue type	Biosample type	Biosample name
Sample_02_181	Human melanoma	Cell line	COLO679
Sample_02_184	Skin	Cell line	SKMEL30

Database name	Link
gnomAD:	gnomAD
ExAC:	ExAC
ICGC:

Database name	Link
Cosmic:
Cosmic cell lines:
Depmap:

TCGA somatic mutations and clinical variants of PKNOX2

rsID	Chr	Start	Stop	Ref	Alt	Gene_region	Gene_symble	Effect	TCGA_Occurrence
-	chr11	125237800	125237800	C	A	exonic	PKNOX2	stopgain	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr11	125280211	125280211	A	G	exonic	PKNOX2	synonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr11	125298943	125298943	C	T	exonic	PKNOX2	synonymous	UCEC\|1\|248\|0.00403
-	chr11	125301229	125301229	G	T	exonic	PKNOX2	stopgain	LUAD\|1\|543\|0.00184
-	chr11	125299914	125299914	G	T	exonic	PKNOX2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr11	125280125	125280125	G	T	exonic	PKNOX2	stopgain	CHOL\|1\|35\|0.02857
-	chr11	125267931	125267931	C	A	exonic	PKNOX2	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
rs758344216	chr11	125255462	125255462	G	A	exonic	PKNOX2	synonymous	BRCA\|1\|982\|0.00102
-	chr11	125255479	125255479	T	G	exonic	PKNOX2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr11	125299995	125299995	G	A	exonic	PKNOX2	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr11	125281707	125281707	C	T	exonic	PKNOX2	synonymous	SKCM\|1\|368\|0.00272
rs758257491	chr11	125281736	125281736	G	A	exonic	PKNOX2	nonsynonymous	PAAD\|1\|185\|0.00541
-	chr11	125281716	125281716	G	A	exonic	PKNOX2	synonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr11	125237806	125237806	C	A	exonic	PKNOX2	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr11	125267941	125267941	A	G	exonic	PKNOX2	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr11	125301253	125301253	G	T	exonic	PKNOX2	nonsynonymous	LUAD\|4\|543\|0.00737
-	chr11	125300029	125300029	A	T	exonic	PKNOX2	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr11	125280723	125280723	T	C	exonic	PKNOX2	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr11	125301169	125301169	G	T	exonic	PKNOX2	stopgain	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr11	125300008	125300008	A	C	exonic	PKNOX2	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRC\|1\|451\|0.00222
rs373672970	chr11	125255595	125255595	G	A	exonic	PKNOX2	nonsynonymous	ACC\|1\|90\|0.01111,COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr11	125300002	125300002	A	T	exonic	PKNOX2	nonsynonymous	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr11	125267956	125267956	C	G	exonic	PKNOX2	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr11	125280103	125280103	G	A	exonic	PKNOX2	synonymous	LUAD\|1\|543\|0.00184
rs750281653	chr11	125281735	125281735	C	T	exonic	PKNOX2	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr11	125281739	125281739	C	T	exonic	PKNOX2	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr11	125301195	125301195	G	T	exonic	PKNOX2	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr11	125237794	125237794	C	-	exonic	PKNOX2	frameshift	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr11	125280766	125280766	C	-	exonic	PKNOX2	frameshift	LUAD\|1\|543\|0.00184
rs778476842	chr11	125299947	125299947	C	T	exonic	PKNOX2	stopgain	HNSC\|1\|512\|0.00195
-	chr11	125300031	125300031	C	A	exonic	PKNOX2	nonsynonymous	LUAD\|6\|543\|0.01105
-	chr11	125280693	125280693	C	T	exonic	PKNOX2	nonsynonymous	KIPAN\|1\|799\|0.00125,KIRP\|1\|282\|0.00355
-	chr11	125301095	125301095	C	G	exonic	PKNOX2	nonsynonymous	BRCA\|1\|982\|0.00102
-	chr11	125221210	125221210	A	G	exonic	PKNOX2	synonymous	LUAD\|1\|543\|0.00184
rs768234237	chr11	125280187	125280187	C	T	exonic	PKNOX2	synonymous	LUAD\|1\|543\|0.00184
-	chr11	125301206	125301206	A	T	exonic	PKNOX2	nonsynonymous	PCPG\|1\|184\|0.00543
-	chr11	125267910	125267910	-	G	exonic	PKNOX2	frameshift	KIPAN\|3\|799\|0.00375,KIRC\|3\|451\|0.00665
-	chr11	125267805	125267805	G	T	exonic	PKNOX2	synonymous	HNSC\|1\|512\|0.00195
-	chr11	125299861	125299861	T	A	exonic	PKNOX2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr11	125267785	125267785	C	T	exonic	PKNOX2	stopgain	SKCM\|1\|368\|0.00272
-	chr11	125299894	125299894	T	C	exonic	PKNOX2	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr11	125301267	125301267	A	G	exonic	PKNOX2	synonymous	PAAD\|1\|185\|0.00541
-	chr11	125237868	125237868	C	T	exonic	PKNOX2	stopgain	BRCA\|2\|982\|0.00204
-	chr11	125221229	125221229	G	A	exonic	PKNOX2	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr11	125300009	125300009	G	A	exonic	PKNOX2	synonymous	OV\|1\|469\|0.00213
-	chr11	125280125	125280125	G	C	exonic	PKNOX2	nonsynonymous	BLCA\|1\|396\|0.00253,CESC\|1\|194\|0.00515
-	chr11	125301156	125301156	G	A	exonic	PKNOX2	synonymous	SKCM\|1\|368\|0.00272
-	chr11	125221269	125221269	C	T	exonic	PKNOX2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr11	125301348	125301348	C	T	UTR3	PKNOX2	unknown	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
rs763656834	chr11	125255525	125255525	C	T	exonic	PKNOX2	synonymous	LUAD\|1\|543\|0.00184,UCEC\|1\|248\|0.00403
rs770561983	chr11	125237753	125237753	C	T	exonic	PKNOX2	synonymous	LIHC\|1\|373\|0.00268
-	chr11	125280153	125280153	T	C	exonic	PKNOX2	nonsynonymous	BRCA\|1\|982\|0.00102
rs763390527	chr11	125301338	125301338	G	A	UTR3	PKNOX2	unknown	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr11	125301131	125301131	T	C	exonic	PKNOX2	nonsynonymous	LUSC\|1\|178\|0.00562
rs746656386	chr11	125280123	125280123	C	T	exonic	PKNOX2	nonsynonymous	LUSC\|1\|178\|0.00562
-	chr11	125267885	125267885	G	A	exonic	PKNOX2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr11	125267790	125267790	C	A	exonic	PKNOX2	synonymous	LUSC\|1\|178\|0.00562
-	chr11	125267928	125267928	C	A	exonic	PKNOX2	synonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr11	125298937	125298937	G	T	exonic	PKNOX2	nonsynonymous	BLCA\|1\|396\|0.00253
-	chr11	125128900	125128900	G	T	intronic	PKNOX2	unknown	CESC\|1\|194\|0.00515
-	chr11	125280738	125280738	T	C	exonic	PKNOX2	nonsynonymous	COAD\|1\|367\|0.00272,COADREAD\|1\|489\|0.00204
-	chr11	125255570	125255570	A	G	exonic	PKNOX2	synonymous	LUAD\|1\|543\|0.00184
rs201383194	chr11	125255470	125255470	C	T	exonic	PKNOX2	nonsynonymous	GBM\|1\|290\|0.00345,GBMLGG\|1\|820\|0.00122
-	chr11	125221274	125221274	C	A	exonic	PKNOX2	nonsynonymous	SARC\|1\|247\|0.00405
rs763253785	chr11	125299879	125299879	G	A	exonic	PKNOX2	nonsynonymous	GBMLGG\|1\|820\|0.00122,LGG\|1\|530\|0.00189
-	chr11	125237849	125237849	C	T	exonic	PKNOX2	synonymous	SKCM\|1\|368\|0.00272
-	chr11	125255455	125255455	T	-	exonic	PKNOX2	frameshift	LUAD\|1\|543\|0.00184
-	chr11	125301240	125301240	G	A	exonic	PKNOX2	synonymous	UCS\|1\|57\|0.01754
-	chr11	125221240	125221240	G	C	exonic	PKNOX2	nonsynonymous	OV\|1\|469\|0.00213
-	chr11	125281699	125281699	C	T	exonic	PKNOX2	stopgain	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr11	125301239	125301239	C	T	exonic	PKNOX2	nonsynonymous	BRCA\|1\|982\|0.00102
rs572689602	chr11	125280125	125280125	G	A	exonic	PKNOX2	nonsynonymous	LUAD\|1\|543\|0.00184,PAAD\|1\|185\|0.00541
-	chr11	125237760	125237760	C	A	exonic	PKNOX2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr11	125237800	125237800	C	T	exonic	PKNOX2	nonsynonymous	OV\|1\|469\|0.00213
-	chr11	125237800	125237800	C	G	exonic	PKNOX2	stopgain	BLCA\|1\|396\|0.00253
-	chr11	125267823	125267823	C	T	exonic	PKNOX2	synonymous	PAAD\|1\|185\|0.00541
-	chr11	125255503	125255503	A	T	exonic	PKNOX2	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr11	125221252	125221252	G	T	exonic	PKNOX2	nonsynonymous	UCEC\|1\|248\|0.00403
-	chr11	125255501	125255501	C	A	exonic	PKNOX2	synonymous	LUAD\|1\|543\|0.00184
-	chr11	125280117	125280117	C	T	exonic	PKNOX2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr11	125301174	125301174	G	T	exonic	PKNOX2	nonsynonymous	COADREAD\|1\|489\|0.00204,READ\|1\|122\|0.00820
-	chr11	125298986	125298986	T	C	splicing	PKNOX2	splicing	STAD\|1\|395\|0.00253,STES\|1\|395\|0.00253
-	chr11	125301354	125301354	G	-	UTR3	PKNOX2	unknown	ESCA\|1\|185\|0.00541,STAD\|4\|395\|0.01013,STES\|4\|395\|0.01013
-	chr11	125301235	125301235	C	T	exonic	PKNOX2	stopgain	HNSC\|1\|512\|0.00195
-	chr11	125301194	125301195	AG	-	exonic	PKNOX2	frameshift	SARC\|1\|247\|0.00405
-	chr11	125300009	125300009	G	T	exonic	PKNOX2	nonsynonymous	LUAD\|2\|543\|0.00368
-	chr11	125221258	125221258	C	A	exonic	PKNOX2	synonymous	BLCA\|1\|396\|0.00253
-	chr11	125299986	125299986	G	T	exonic	PKNOX2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr11	125267908	125267908	C	A	exonic	PKNOX2	nonsynonymous	LUAD\|2\|543\|0.00368
-	chr11	125300032	125300032	C	T	exonic	PKNOX2	nonsynonymous	SKCM\|1\|368\|0.00272
rs146936477	chr11	125301144	125301144	C	T	exonic	PKNOX2	synonymous	UCEC\|1\|248\|0.00403
-	chr11	125267917	125267917	C	T	exonic	PKNOX2	nonsynonymous	LUAD\|1\|543\|0.00184
-	chr11	125237848	125237848	C	T	exonic	PKNOX2	nonsynonymous	SKCM\|1\|368\|0.00272
-	chr11	125280751	125280751	C	A	exonic	PKNOX2	synonymous	LUAD\|1\|543\|0.00184
-	chr11	125255507	125255507	C	A	exonic	PKNOX2	synonymous	PAAD\|1\|185\|0.00541
rs750944288	chr11	125301145	125301145	G	A	exonic	PKNOX2	nonsynonymous	HNSC\|1\|512\|0.00195
-	chr11	125301195	125301195	G	A	exonic	PKNOX2	synonymous	ESCA\|1\|185\|0.00541
-	chr11	125221244	125221244	G	A	exonic	PKNOX2	nonsynonymous	PRAD\|1\|499\|0.00200
-	chr11	125299921	125299921	C	A	exonic	PKNOX2	nonsynonymous	LUAD\|6\|543\|0.01105
-	chr11	125237764	125237764	C	T	exonic	PKNOX2	nonsynonymous	LIHC\|1\|373\|0.00268
-	chr11	125301355	125301355	G	A	UTR3	PKNOX2	unknown	ESCA\|1\|185\|0.00541
-	chr11	125281668	125281668	G	A	exonic	PKNOX2	synonymous	BLCA\|1\|396\|0.00253
rs200769767	chr11	125281675	125281675	G	A	exonic	PKNOX2	nonsynonymous	BLCA\|1\|396\|0.00253

TF name:	PKNOX2
TF family:	Homeobox
Ensembl gene ID:	ENSG00000165495
Ensembl protein ID:	ENSP00000298282
Entrez gene ID:	63876

Database name	Link	Database name	Link
NCBI Gene:		Genecards:
Uniprot:		Wikipedia:
Cosmic 3D:		Geneontology:
CCLE:

TF_name	Disease_name	Disease_class	Disease_semantic_type	TF_disease_source
PKNOX2	Alcoholic Intoxication, Chronic	C25;F03	Mental or Behavioral Dysfunction	PSYGENET
PKNOX2	Schizophrenia	F03	Mental or Behavioral Dysfunction	PSYGENET

GO_term_name	GO_term_type	TF_name
GO_ACTIN_FILAMENT_BINDING	MF	PKNOX2
GO_ACTIN_MONOMER_BINDING	MF	PKNOX2

TF information

TCGA somatic mutations and clinical variants of PKNOX2

Survival analysis of PKNOX2

Expression of PKNOX2