not only provides comprehensive gene expression information
for T(co)F target genes of interest, but also collects upstream pathway information
for T(co)Fs and various functional annotation information
for downstream target genes, such as GO/KEGG pathway enrichment, hierarchical clustering analysis and differentially expressed analysis. Furthermore, KnockTF 2.0
collects the detailed and abundant (epi)genetic annotation information
for T(co)F target genes, including super-enhancers, enhancers, transcription factor binding sites (TFBSs), common SNPs, risk SNPs, expression quantitative trait locus (eQTL), methylation sites, DNase I hypersensitivity sites (DHSs), chromatin interactions, chromatin accessibility regions, CRISPR/Cas9 target sites, and topologically associating domains (TADs).
provides a conveniently, user-friendly interface for querying, browsing, analyzing and downloading detailed information about gene expression profiles of T(co)F knockdown/knockout datasets.