What is eRNAbase?
Enhancer RNA (eRNA) is a type of transcribed RNA from distal enhancers, which plays key roles in
transcription regulatory circuitry to mediate the activation of target gene. Here, we developed the eRNA
database (eRNAbase), which aims to document a large number of available resources of
human and mouse eRNAs, provide comprehensive annotation and analyses
for eRNAs.
The current version of eRNAbase cataloged a total of 10,399,928 eRNAs from 1,012 samples including 858 human samples and 154 mouse samples. Emphatically, eRNAbase provides the detailed and abundant (epi) genetic annotations in ChIP-seq based eRNA regions, such as super enhancer, enhancer, common SNPs, motif changes, expression quantitative trait locus (eQTL), risk SNPs, transcription factor binding sites (TFBSs), CRISPR/Cas9 target sites, DNase I hypersensitivity sites (DHSs), chromatin accessibility regions, methylation sites, chromatin interactions regions and TADs. eRNAbase also provides eRNA-associated downstream target genes by mapping eRNA regions into genomes via five methods. We believe that eRNAbase could become a useful and effective platform for exploring potential functions and regulation of eRNAs in diseases and biological processes.
Data distribution
Principal Investigator: Chunquan Li, Ph.D.
The First Affiliated Hospital, Hengyang Medical School, University of South China
Email: lcqbio@163.com
We welcome researchers from all over the world to provide valuable advice for eRNAbase, and make eRNAbase more and more perfect.
Statistics
| Human | Mouse | |
|---|---|---|
| eRNAs | 9155797 | 1244131 |
| Samples | 858 | 154 |
| Experiment Type | 14 | 10 |
| Tissues | 39 | 11 |
| Cells | 116 | 36 |
LncSEA
LncSEA: A comprehensive human lncRNA sets resource and enrichment analysis platform
TcoFbase
Document a large number of available resources of mammals TcoFs
SEdb
SEdb: The comprehensive human Super-Enhancer databasebr
SEanalysis
SEanalysis: a web tool for super-enhancer associated regulatory analysis
ENdb
ENdb: An experimentally supported enhancer database for human and mouse
VARAdb
VARAdb: A comprehensive human variation annotation database
TRlnc
TRlnc: A comprehensive database of human transcriptional regulation of lncRNAs
TRCirc
TRCirc: A resource for transcriptional regulation information of circRNAs
ATACdb
ATACdb: A comprehensive human chromatin accessibility database
KnockTF
KnockTF: a comprehensive human gene expression profile database with knockdown/knockout of
transcription factors