If users input of a set of genes of interest, eRNAbase will identify upstream pathways that are significantly enriched by hypergeometric test. In each pathway, eRNAbase will locate the terminal TFs and extract the terminal TF bound downstream eRNAs.

1) Databases: Select at least one database of pathways.

2) Genes: Input a gene symbol set.

3) Threshold: Set P-Value and FDR thresholds.

4) GeneNumber: Limit the number range of genes in pathways.