External factors: | TSG |
Aging type: | Prevent |
Aging characteristic: |
Category: | Chemical compounds |
Phenotype: | Aging |
Experiment: | SA-β-gal activity assay//Western blot |
Description: | The results revealed that TSG pretreatment could reduce the percentage of senescence-associated-β-galactosidase (SA-β-gal) positive cells, and decrease the expression levels of the cellular senescence biomarkers, p53 and PAI-1 proteins. |
Target gene: | SIRT1 |
R-EF-Target gene: | Upregulation |
Official symbol(s): | SIRT1 |
Target gene experiment: | Western blot |
Target gene description: | Representative images of WB analysis and the semi‐quantification of SIRT1 and E2F1 in HUVECs. |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: