Aging Overview

External factors

External factors: TSG
Aging type: Prevent
Aging characteristic:
Category: Chemical compounds
Phenotype: Aging
Experimental category: L
Tissue type: --
Cell name: HUVEC
PMID: 32898442
Experiment: SA-β-gal activity assay//Western blot
Description: The results revealed that TSG pretreatment could reduce the percentage of senescence-associated-β-galactosidase (SA-β-gal) positive cells, and decrease the expression levels of the cellular senescence biomarkers, p53 and PAI-1 proteins.


Regulatory relationship

Target gene: SIRT1
R-EF-Target gene: Upregulation
Official symbol(s): SIRT1
Target gene experiment: Western blot
Target gene description: Representative images of WB analysis and the semi‐quantification of SIRT1 and E2F1 in HUVECs.

Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.