| External factors: | UA |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Cateract |
| Experiment: | SA-β-gal activity assay |
| Description: | Assay for the senescence marker, SA-β-gal, showed the presence of blue labels for SA-β-gal in the cytoplasm of UA-treated cells. Such staining was not detected in cells treated without UA in the controls. The percentage of SA-β-gal positive cells were 5.27 ± 0.97% in cells treated with 50 μM UA, 17.22 ± 2.67% in 100 μM group, and 23.04 ± 7.42% in 200 μM group, showing a dose dependent increase in senescent cells after UA treatment. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: