| External factors: | UVB |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Other |
| Phenotype: | Aging |
| Experiment: | Western blot |
| Description: | We found that UVB exposure increased the levels of γH2AX, p16INK4A, and cleaved caspase-3 in the epidermis of wild-type mice, indicating increased senescence and apoptosis. Furthermore,the induction of γH2AX, p16INK4A, and cleaved caspase-3 levels was attenuated in TRPC7+/? and TRPC7?/? mice. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: