| External factors: | Radiation |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Other |
| Phenotype: | Chronic myeloid leukemia |
| Experiment: | SA-β-gal activity assay//Flow cytometry |
| Description: | After 5-day incubation, a substantial part of irradiated cells underwent phenotypic changes characteristic of senescence, associated with β-galactosidase staining. At the concentration used, STI571 alone did not induce such changes.Radiation alone induced a depletion of the G1- and S-phase compartments together with prolonged accumulation in the G2 phase. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: