External factors: | Zn |
Aging type: | Accelerate |
Aging characteristic: |
Category: | Other |
Phenotype: | Aging |
Experiment: | SA-β-gal activity assay//Flow cytometry//qRT-PCR//Western blot |
Description: | Almost all Zn-treated cells (approximately 90%) had undergone cell death by passage 11, whereas only approximately 40% of control cells had undergone cell death by this point. Measurement of SA-β-gal staining and p16 expression as biomarkers of senescence revealed increases induced by the Zn treatment at late passages. |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: