| External factors: | Sulfur mustard |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Other |
| Phenotype: | Chronic wound healing |
| Experiment: | SA-β-gal activity assay |
| Description: | Using a SM concentration of 40 μM (IC25), most of the MSC demonstrate a senescence typical expression of ?-galactosidase.In absence of SM, 37.0 ± 1.2% of all cells were positive for Ki-67 within the nucleus. With increasing concentration of SM the number of Ki-67 positive nucleus deceased to 0.8 ± 0.1% at IC25(40 μM). Under exposure of IC1(1 μM) the number of proliferating cells were decreased by 26%. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: