Aging Overview

External factors

External factors: Fibroblast-Derived Extracellular Matrix
Aging type: Prevent
Aging characteristic:
Category: Other
Phenotype: Aging
Experimental category: L
Tissue type: Adipose
Cell name: ad-MSC
PMID: 27527147
Experiment: qRT-PCR//Western blot
Description: The average population doubling time for ad-MSCs on the fd-ECM increased significantly.Gene expression of several anti-senescence markers was significantly upregulated in ad-MSCs cultured on fd-ECM .The expression of several genes such as P16, P21, and P53 was downregulated in the presence of fd-ECM .


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.