| External factors: | High glucose |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Other |
| Phenotype: | Type 2 diabetes mellitus |
| Experiment: | SA-β-gal activity assay//Cell morphological analysis |
| Description: | Accordingly, the percentage of senescent EC reached a significant level after 48 h of treatment with hGluc (44.271.31% vs. 18.171.52% in Ctr, Po0.01). SA β-gal positive cells in samples co-treated with EgtthGluc were 28.371.22% vs. 44.271.31% in hGluc (Po0.01). Moreover, microscopy examination revealed that the hGluc senescent EC become large and with more spindle-shaped morphology. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: