Aging Overview

External factors

External factors: Irradiation
Aging type: Accelerate
Aging characteristic:
Category: Other
Phenotype: Aging
Experimental category: L
Tissue type: --
Cell name: A549,H1299
PMID: 27341700
Experiment: SA-β-gal activity assay//Western blot
Description: For cellular senescence analysis, an SA-βGal assay in NSCLC cells was performed 3 days after irradiation. SA-βGal–positive cells increased significantly in carbon-irradiated A549 cells and in H1299 cells treated with NU7441 and carbon irradiation.p21 expression in A549 cells was consistent with the result of the SA-βGal assay; in contrast, no activation was observed in H1299 cells.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.