Aging Overview

External factors

External factors: Human respiratory syncytial virus
Aging type: Accelerate
Aging characteristic:
Category: Other
Phenotype: Aging
Experimental category: L
Tissue type: Lung
Cell name: HEp-2,A549
PMID: 26809688
Experiment: SA-β-gal activity assay
Description: We observed that the infection of A549 and HEp-2 cells by HRSV induces the accumulation of senescent cells positive forSA-β-gal activity. This activity could also be detected in spontaneous syncytia of both immortalized cell lines ( 20-40%) but was greatly magnified in both mononuclear cells and syncytia upon HRSV infection.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.