External factors: | Human respiratory syncytial virus |
Aging type: | Accelerate |
Aging characteristic: |
Category: | Other |
Phenotype: | Aging |
Experiment: | SA-β-gal activity assay |
Description: | We observed that the infection of A549 and HEp-2 cells by HRSV induces the accumulation of senescent cells positive forSA-β-gal activity. This activity could also be detected in spontaneous syncytia of both immortalized cell lines ( 20-40%) but was greatly magnified in both mononuclear cells and syncytia upon HRSV infection. |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: