Aging Overview

External factors

External factors: Ionizing radiation
Aging type: Accelerate
Aging characteristic:
Category: Other
Phenotype: Aging
Experimental category: L
Tissue type: --
Cell name: MRC-5
PMID: 20160708
Experiment: SA-β-gal activity assay//BrdU assay//Immunostaining
Description: This abolished cell growth and labelling indices for BrdU, Ki67 and caused expression of senescence-associated β-galactosidase (Sen-β-Gal) to an extent equal to the deep replicative senescence seen when cells had reached their normal proliferative limit.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.