External factors: | Ionizing radiation |
Aging type: | Accelerate |
Aging characteristic: |
Category: | Other |
Phenotype: | Aging |
Experiment: | SA-β-gal activity assay//BrdU assay//Immunostaining |
Description: | This abolished cell growth and labelling indices for BrdU, Ki67 and caused expression of senescence-associated β-galactosidase (Sen-β-Gal) to an extent equal to the deep replicative senescence seen when cells had reached their normal proliferative limit. |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: