| External factors: | Ionizing radiation |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Other |
| Phenotype: | Aging |
| Experiment: | SA-β-gal activity assay//Western blot |
| Description: | IR-exposed MCF7 cells exhibited specific characteristics of cellular senescence, such as enlarged, flattened morphological changes and positive senescence-associated β-galactosidase staining. These cells also showed pRb hypophosphorylation, p53 accumulation and p21 induction in western blot analyses. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: