Aging Overview

External factors

External factors: Antioxidant
Aging type: Prevent
Aging characteristic:
Category: Chemical compounds
Phenotype: Cornelia de Lange syndrome
Experimental category: HL
Tissue type: --
Cell name: CdLS 417,CdLS 565
PMID: 29860495
Experiment: SA-β-gal activity assay
Description: We found that both antioxidant drugs independently increased the number of passages the cells made in vitro by about 50%, using untreated CdLS cell as control for lifespan . These data are further supported by the decrease in both the number of β-galactosidase positive cells(data not shown) and their staining intensity.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.