| External factors: | LPD |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Hepatocellular carcinoma |
| Experiment: | SA-β-gal activity assay |
| Description: | The cell senescence induced by LPD in SMMC-7721 and HepG2 cells.In HepG2 cells with wild-type p53 which is essential for inducing senescence,increased SA-β-gal staining relative to NC-LPD was observed after treatment with RRM2-LPD. More SA-β-gal-positive cells were observed in the ADR-NC-LPD treated group, whereas the ADRRRM2-LPD treated group possessed the most SA-β-gal-positive cells. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: