Aging Overview

External factors

External factors: TBHP
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Osteoarthritis
Experimental category: L
Tissue type: --
Cell name: Primary mice Chondrocyte,Primary human Chondrocyte
PMID: 30154423
Experiment: SA-β-gal activity assay//Western blot
Description: The TBHP-treated chondrocytes exerted higher SA-β-gal activity and p16INK4a protein level relative to the control group, whereas TFEB overexpression significantly prevents this increment.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.