| External factors: | MLN4924 |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Renal carcinoma |
| Experiment: | SA-β-gal activity assay//Flow cytometry |
| Description: | The results suggested that the low concentration of MLN4924 (0.1 μM) affected the cell-cycle distribution moderately and the high concentrations (0.5 μM) increased the G2 phase population . Results confirmed MLN4924induced senescence as most renal cancer cells were stained after MLN4924 treatment by β-galactosidase staining assay. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: