Aging Overview

External factors

External factors: Midostaurin
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Lung cancer
Experimental category: HL
Tissue type: --
Cell name: KRAS-mutant cell
PMID: 25667133
Experiment: SA-β-gal activity assay
Description: Midostaurin also increased the number of residual IR-induced DNA double-strand breaks and caused apoptosis and senescence in irradiated KRAS-mutant cells.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.