Aging Overview

External factors

External factors: CHCl3:Me-OH
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Aging
Experimental category: L
Tissue type: --
Cell name: HDF
PMID: 26161621
Experiment: SA-β-gal activity assay
Description: Organic solvent (CHCl3:Me-OH) caused a 3-fold increase in the number of SA-β-gal positive cells (photo b) but 42% decrease in overall cell number than the control (photo a), indicating that the organic solvent had strong cytotoxic and pro-senescent effects.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.