External factors: | Adriamycin |
Aging type: | Accelerate |
Aging characteristic: |
Category: | Chemical compounds |
Phenotype: | Aging |
Experiment: | SA-β-gal activity assay//Flow cytometry |
Description: | About 50% of the attached cells became senescent after 3 days of Adriamycin treatment. cells were arrested with hydroxyurea, released, and further treated with 30 nmol/L Adriamycin for 5 to 25 hours. Whereas control cells remained growth arrested, 15% of Src-expressing cells had already progressed into mitosis by 10 hours. |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: