Aging Overview

External factors

External factors: Idebenone
Aging type: Prevent
Aging characteristic:
Category: Chemical compounds
Phenotype: Glaucoma
Experimental category: L
Tissue type: Eye
Cell name: Human lamina cribrosa Astrocyte
PMID: 23661043
Experiment: SA-β-gal activity assay
Description: A significantly reduced SA -β-Gal activity was noted when cells were pretreated with 10mM idebenone and then exposed to 600mM H2O2.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.