Aging Overview

External factors

External factors: Everolimus
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Diffuse intrinsic pontine glioma
Experimental category: HL
Tissue type: Tumor tissue
Cell name: DIPG 4,SF7761
PMID: 29207163
Experiment: SA-β-gal activity assay
Description: Effects of everolimus and AZD2014 on senescence, as measured by the percentage of cells staining positive for β-galactosidase.here, both compounds appeared to increase the percentage of senescent cells in a dose-dependent manner, but there was no clear difference between the two.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.