| External factors: | Tamoxifen |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Glioma |
| Experiment: | SA-β-gal activity assay |
| Description: | We found that treatment of cells with TAM alone induced senescence, whereas combination of TAM + OV augmented OV-mediated cytotoxicity (oncolytic cell killing), as revealed by inhibition of cell proliferation (~36% decrease vs. mock, p = < 0.001) and decreased the number of β-gal-positive senescent cells relative to treatment with OV alone. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: