Aging Overview

External factors

External factors: 4-hydroxynonenal
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Retinal damage
Experimental category: L
Tissue type: --
Cell name: ARPE?19
PMID: 31070214
Experiment: SA-β-gal activity assay
Description: The positive staining of β-galactosidase was significantly greater after 30 μM HNE treatment, and the proportion of positively stained cells reached 52.0% ± 4.8%.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.