Aging Overview

External factors

External factors: Metformin
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Squamous cell carcinoma
Experimental category: L
Tissue type: Tumor tissue
Cell name: --
PMID: 28185288
Experiment: SA-β-gal activity assay
Description: Average staining intensity of stromal GALB, which is a marker of senescence, increased from 32.4% to 50.2% after treatment with metformin.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.