External factors: | Bleomycin |
Aging type: | Accelerate |
Aging characteristic: |
Category: | Chemical compounds |
Phenotype: | Idiopathic pulmonary fibrosis |
Experiment: | Western blot//qRT-PCR |
Description: | In ex vivo experiments, we found that lung epithelial cells of bleomycin-treated WT aged mice demonstrated increased senescent phenotype, as evidenced by greater expression of p21 and PAI-1 in these cells. |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: