Aging Overview

External factors

External factors: EX527
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Pancreatic cancer
Experimental category: L
Tissue type: --
Cell name: PANC-1
PMID: 25843411
Experiment: SA-β-gal activity assay
Description: Cellular senescence was determined using SA-β-gal staining on Day 6 and Day 9. EX527 and GEM alone induced cellular senenscence compared to Control, however their combination treatment did not result in any synergistic effect.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.