Aging Overview

External factors

External factors: Erlotinib
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Cervical cancer
Experimental category: L
Tissue type: Cervical
Cell name: Epithelial cell
PMID: 21982220
Experiment: SA-β-gal activity assay
Description: The ability to form colonies decreased strongly after cells were treated with erlotinib for 6 8 days. During this time, a large percentage of surviving cells became positive for β-galactosidase , a marker for cell senescence.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.