Aging Overview

External factors

External factors: MTX
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Melanoma
Experimental category: HL
Tissue type: --
Cell name: Melanoma cell
PMID: 24862567
Experiment: SA-β-gal activity assay
Description: MTX treatment also induced senescence in melanoma cells as evident by the induction of β-galactosidase activity with post 48 h MTX treatment at 5 μM, with an additional 72 h rescuing of cells in regular medium .


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.