External factors: | Chloramphenicol |
Aging type: | Accelerate |
Aging characteristic: |
Category: | Chemical compounds |
Phenotype: | Aging |
Experiment: | SA-β-gal activity assay//Cell morphological analysis |
Description: | The photographic images show morphological changes in chloramphenicol-treated H1299 cells. Both cells show blue-violet X-gal crystal accumulation in senescence-associated β-galactosidase staining, suggesting that chloramphenicol-associated mitochondrial stress might trigger senescence biogenesis.The morphology of these chloramphenicol-treated cells was changed to the more flattened, enlarged, and irregular shape characteristic of cell senescence. |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: