Aging Overview

External factors

External factors: Antimitotic drugs
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Colorectal cancer
Experimental category: HL
Tissue type: --
Cell name: HCT116
PMID: 30037855
Experiment: SA-β-gal activity assay
Description: SA-β-gal staining showed discernible differences in the extent of senescence,as PTX and ZM significantly increased the percentage of SA-β-gal positive-cells while Mon-treated cells hardly displayed signs of senescence. Increased SA-β-gal staining was also observed for Noc- and PTX-treated HCT116 cells.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.