Aging Overview

External factors

External factors: ATO
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Aging
Experimental category: L
Tissue type: Blood
Cell name: MSC
PMID: 21257625
Experiment: SA-β-gal activity assay
Description: The SA-β-gal staining results showed that 1 mM ATO induced senescence of MSCs.There were almost no senescent cells in control whereas the percentages of senescent cells were about 50%-70% in MSCs treated with 1 mM ATO .


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.