| External factors: | Berberine |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Lung cancer |
| Experiment: | SA-β-gal activity assay//Flow cytometry |
| Description: | Berberine treatment at 3.125 μM and 6.25 μM concentration induced a significant (P < 0.05) increase in SA-β-gal activity in A549 cells as compared to control.These microscopic observations were also corroborated by flow cytometry data wherein a significant (P < 0.05) decrease in mean pixel bright field intensity was observed in cells exposed to 3.125–12.5 μM berberine, while the effect seemed to decrease albeit non-significantly at higher concentrations. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: