External factors: | TBHP |
Aging type: | Accelerate |
Aging characteristic: |
Category: | Chemical compounds |
Phenotype: | Aging |
Experiment: | SA-β-gal activity assay//Comet assay//Western blot |
Description: | Exposure of HUVECs to 55 μmol/l tBHP increased the percentage of senescent cells 3.8-fold tBHP-induced DNA damage, as shown by the increased olive tail moment of the comet assay, and up-regulated p21 protein expression. |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: