Aging Overview

External factors

External factors: TBHP
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Aging
Experimental category: L
Tissue type: --
Cell name: HUVEC
PMID: 22563892
Experiment: SA-β-gal activity assay//Comet assay//Western blot
Description: Exposure of HUVECs to 55 μmol/l tBHP increased the percentage of senescent cells 3.8-fold tBHP-induced DNA damage, as shown by the increased olive tail moment of the comet assay, and up-regulated p21 protein expression.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.