| External factors: | Pan-mTOR inhibitors |
| Aging type: | Prevent |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | SA-β-gal activity assay//Cell morphological analysis |
| Description: | Treatment with PD0332991 caused senescent morphology in SKBR3 cells. Co-treatment with pan-mTOR inhibitors prevented senescent morphology and hypertrophy.Pan-mTOR inhibitors also prevented senescent morphology of MEL10 cells induced to senesce by treatment with low concentration of nutlin-3a. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: