| External factors: | Rapamycin |
| Aging type: | Prevent |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | MTT assay//SA-β-gal activity assay//Western blot |
| Description: | After treatment with rapamycin, proliferation of all senescent cells was dose-dependent, with the highest cell viability observed at 25 nm rapamycin. When cells were treated with rapamycin,a reduction in SA-β-gal-positive cells was observed(19.39?±?2.42%).Western blot analysis showed a significant decrease in the levels of p53 and p21 after treatment with rapamycin. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: