External factors: | Estrogen |
Aging type: | Prevent |
Aging characteristic: |
Category: | Chemical compounds |
Phenotype: | Aging |
Experiment: | Telomere length assay//Southern blot |
Description: | Telomere length declined over the entire observation period for all experimental groups to values ranging from 6.4 to 9.8 kbp,with increasing concentrations of E2 treatment, mean telomere shortening decreased(MSCs).Telomere length declined for all experimental groups to values ranging from 8.2 to 10.2 kbp. Telomere shortening correlated with cpd (P < 0.001). With increasing concentrations of E2 treatment, mean telomere shortening decreased(Human chondrocytes). |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: