| External factors: | Probucol |
| Aging type: | Prevent |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | SA-β-gal activity assay//Western blot |
| Description: | Probucol pretreatment significantly decreased the rate of positive β-galactosidase staining in human glomerular mesangial cells exposed to Ang II;Additionally,probucol significantly inhibited the Ang II-induced expression of the senescence-related proteins p53 and p21. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: