External factors: | Ang II |
Aging type: | Accelerate |
Aging characteristic: |
Category: | Chemical compounds |
Phenotype: | Aging |
Experiment: | Western blot//SA-β-gal activity assay |
Description: | Compared with the normal control group, the western blotting analysis showed that the expression levels of the senescence-related proteins p53 and p21 rose gradually as the duration of the 10-6 mmol/L Ang II treatment increased. The rate of positive β-galactosidase staining reached 65.43±1.31% after treatment of Ang II for 72 h, which was significantly higher than the rate obtained in the normal control group. |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: