Aging Overview

External factors

External factors: Doxorubicin
Aging type: Accelerate
Aging characteristic:
Category: Chemical compounds
Phenotype: Aging
Experimental category: L
Tissue type: --
Cell name: HepG2
PMID: 31942817
Experiment: SA-β-gal activity assay
Description: The presence of DOXO induced about 60% of SA β-gal-positive HepG2 cells and 35% of H9c2 cells. The addition of SCIC2 and SCIC2.1 led to a reduction of ~20% and ~15% in the number of SA β-gal-positive HepG2 and H9c2 cells, respectively.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.