Aging Overview

External factors

External factors: Glutathione
Aging type: Prevent
Aging characteristic:
Category: Chemical compounds
Phenotype: Werner syndrome
Experimental category: L
Tissue type: --
Cell name: HeLa
PMID: 24757718
Experiment: SA-β-gal activity assay
Description: Treatment of Hela cells grown under the atmosphere of 1% O2 with GSH prior to WRN depletion improved proliferation and was accompanied by a remarkable reduction in senescence.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.