External factors: | Paclitaxel |
Aging type: | Accelerate |
Aging characteristic: |
Category: | Chemical compounds |
Phenotype: | Gastric cancer |
Experiment: | SA-β-gal activity assay//Flow cytometry |
Description: | SA-β-galactosidase activity staining showed a clear increase in cellular senescence in these cells after PTX treatment compared with control MKN45 cells. PTX causes a prometaphase arrest cell cycle that, if sustained, generates DNA damage and senescence. |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: