| External factors: | Capecitabine |
| Aging type: | Accelerate |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Aging |
| Experiment: | SA-β-gal activity assay |
| Description: | Compared with sera obtained prior to starting capecitabine, those samples taken at the end of treatment significantly increased the frequency of SA β‐gal positive cells.Measurement of sVCAM‐1 and sICAM‐1 concentrations in the same sera revealed that levels of sVCAM‐1 were significantly higher after than before chemotherapy. By contrast, there was no statistically significant elevation in sICAM‐1 values, although a tendency for that direction was noted. Furthermore, concentrations of CD146 significantly increased after treatment. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: