| External factors: | Rapamycin |
| Aging type: | Prevent |
| Aging characteristic: |
| Category: | Chemical compounds |
| Phenotype: | Dyskeratosis congenita |
| Experiment: | SA-β-gal activity assay |
| Description: | We performed ?-galactosidase assays to test if the prolonged survival in the rapamycin treated fibroblast cultures of the patient (II-2) correlated with decreased senescence. We detected decreased senescence in the control fibroblasts, fibroblasts of the mother I-2 and the affected patient II2 at day 30 when treated with rapamycin. |
| Regulatory pathway: | -- |
| R-EF-Pathway: | -- |
| Pathway experiment: | -- |
| Pathway description: | -- |
Annotation: