Aging Overview

External factors

External factors: Resveratrol
Aging type: Prevent
Aging characteristic:
Category: Chemical compounds
Phenotype: Heart failure
Experimental category: L
Tissue type: --
Cell name: HCPC
PMID: 25889431
Experiment: SA-β-gal activity assay//Western blot
Description: However, with respect to DOXO, DOXO + RES co-treatment resulted in a significant reduction in p16INK4a expression (27% vs DOXO). These data were confirmed by a substantial reduction (76% vs DOXO) of β-galactosidase enzymatic activity assay. Thus, the treatment with RES prevented the onset of senescence in hCPCs.


Regulatory pathway: --
R-EF-Pathway: --
Pathway experiment: --
Pathway description: --


Aging network

Annotation:

The green line represents Upregulation.

The purple line represents Downregulation.

The orange line represents Activation.

The yellow line represents Inhibition.

The gray line represents Unclear.