External factors: | Resveratrol |
Aging type: | Prevent |
Aging characteristic: |
Category: | Chemical compounds |
Phenotype: | Heart failure |
Experiment: | SA-β-gal activity assay//Western blot |
Description: | However, with respect to DOXO, DOXO + RES co-treatment resulted in a significant reduction in p16INK4a expression (27% vs DOXO). These data were confirmed by a substantial reduction (76% vs DOXO) of β-galactosidase enzymatic activity assay. Thus, the treatment with RES prevented the onset of senescence in hCPCs. |
Regulatory pathway: | -- |
R-EF-Pathway: | -- |
Pathway experiment: | -- |
Pathway description: | -- |
Annotation: